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Administration

Prof Ofori Kwakye

Prof Prof. Kwabena Ofori-Kwakye

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Research-areas

Prof. K. Ofori-Kwakye is a Pharmacist and an Associate Professor of Pharmaceutics in the Department of Pharmaceutics, Faculty of Pharmacy & Pharmaceutical Sciences, Kwame Nkrumah University of Science & Technology (KNUST), Kumasi, Ghana. He served as Vice-Dean (Aug 2014-Jul 2016) and Head of Department of Pharmaceutics (Aug 2004-Jul 2011; Aug 2012-Jul 2016) at KNUST. Prof. Ofori-Kwakye graduated with Bachelor of Pharmacy Second Class Honours (Upper division) degree from KNUST, in October 1989. He undertook graduate studies at King’s College, University of London and graduated in September 1993 with MSc Pharmaceutical Technology (with Distinction). He was appointed a lecturer in Pharmaceutics at KNUST in January 1994. He pursued doctoral studies at the School of Pharmacy & Pharmaceutical Sciences, University of Manchester, UK, and graduated in 2002 with PhD in Pharmaceutics in the area of Drug Delivery & Dosage Form Design. Prof. Ofori-Kwakye has been a Visiting Scientist and Visiting Associate Professor at the Department of Pharmaceutics, Biopharmaceutics & Nutri-Cosmetics, Freie Universität Berlin, Germany; and the Department of Pharmaceutical Technology, Madonna University, Elele, Rivers State, Nigeria, respectively. He served as external examiner for the Department of Pharmacy, Central University College, Miotso, Ghana for four years. He has been an external assessor/reviewer for academic staff promotion for University of Ghana, Legon, and University of Ibadan, Nigeria. He has supervised several graduate and undergraduate research projects and acted as reviewer for several peer-reviewed journals. He is a member of the Editorial Board of African Journal of Pharmaceutical Sciences and Pharmacy and African Journal of Microbiology Research. He has attended several conferences, workshops, management and leadership courses in countries such as Nigeria, Ethiopia, South Africa, United Kingdom and Germany.  Prof. Ofori-Kwakye is a member of the Pharmaceutical Society of Ghana and a Foundation Fellow of the Ghana College of Pharmacists. He is also a member of Institute of Pharmacy Management, UK; and the American Association of Pharmaceutical Scientists.

 

Research Interests

  • Controlled drug delivery
  • Pharmaceutical nanotechnology
  • Colonic and mucosal drug delivery
  • Tabletting and film coating technology
  • Quality evaluation of antimalarial medicines
  • Formulation and quality control of herbal and orthodox medicines
  • Development of herbal products into acceptable pharmaceutical dosage forms
  • Development of pharmaceutical excipients from local gums and other polymer materials

 

Selected Journal Publications

  1. Fosu M-A, Ofori-Kwakye K, Kuntworbe N, Bonsu MA. (2016). Investigation of blends of cashew and xanthan gums as a potential carrier for colonic delivery of ibuprofen. International Journal of PharmTech Research, 9(7), 369 – 380.
  2. Bonsu MA, Ofori-Kwakye K, Kipo SL, Boakye-Gyasi ME, Fosu M-A. (2016). Development of oral dissolvable films of diclofenac sodium for osteoarthritis using Albizia and Kahaya gums as hydrophilic film formers. Journal of Drug Delivery, volume 2016, Article ID 6459280, 11 pages. http://dx.doi.org/10.1155/2016/6459280

 

  1. Adi-Dako O, Ofori-Kwakye K, Frimpong-Manso S, Boakye-Gyasi M, Sasu C, Pobee M. (2016). Physicochemical and antimicrobial properties of cocoa pod husk pectin intended as a versatile pharmaceutical excipient and nutraceutical. Journal of Pharmaceutics, volume 2016, Article ID 7608693, 12 pages. http://dx.doi.org/10.1155/2016/7608693
  1. Ofori-Kwakye K, Mfoafo KA, Kipo SL, Kuntworbe N, Boakye-Gyasi ME. (2016). Development and evaluation of extended release matrix tablets of two model drugs of different water solubilities by direct compression. Saudi Pharmaceutical Journal, 24, 82 – 91. http://dx.doi.org/10.1016/j.jsps.2015.03.005
  2. Kipo SL, Osei YG, Kuntworbe N, Bayor MT, Ofori-Kwakye K, Boakye-Gyasi ME (2015). Development and in vitro evaluation of oral gels and vaginal pessaries from crude extracts of four Ghanaian medicinal plants intended for the treatment of candidiasis. World Journal of Pharmaceutical Research. World Journal of Pharmaceutical Research, 4 (8), 174 – 194.
  1. Sougi A, Ofori-Kwakye K, Kuntworbe N, Kipo SL, Boakye-Gyasi ME. (2015). Evaluation of the physicochemical properties of metformin hydrochloride tablet brands marketed in five cities in Ghana. British Journal of Pharmaceutical Research, 9 (1), 1 – 14. DOI : 10.9734/BJPR/2016/21862

 

  1. Kipo SL, Osei-Asare C, Ofori-Kwakye K, Buabeng KO, Anto BP (2015). Physician and patient preferences for sustained release antihypertensive preparations in the Kumasi metropolis, Ghana. West African Journal of Pharmacy, 26 (1), 1-10.

 

  1. Osei-Asare C, Kipo SL, Ofori-Kwakye KBoakye-Gyasi ME (2015). Comparative in vitro dissolution of commercially available sustained release nifedipine tablet brands in the Kumasi Metropolis, Ghana. Journal of Applied Pharmaceutical Science, 5 (08), 054-060. DOI: 10.7324/JAPS.2015.50809

 

  1. Kumadoh D, Adotey J, Ofori-Kwakye K, Kipo SL, Prah T, Patterson S. (2015). Development of oral capsules from enterica herbal decoction – a traditional remedy for typhoid fever in Ghana. Journal of Applied Pharmaceutical Science, 5(04), 083 – 088. DOI: 10.7324/JAPS.2015.50414

 

  1. Kipo SL, Oppong EE, Ofori-Kwakye K.  (2014). Physicochemical evaluation and tablet formulation properties of shea tree gum. Asian Journal of Pharmaceutical and Clinical Research 7 (5), 121 – 127.

 

  1. Frimpong G, Adotey J, Ofori-Kwakye K, Kipo SL, Dwomo-Fokuo Y. (2014). Potential of aqueous extract of Hibiscus sabdariffa calyces as coloring agent in three pediatric oral pharmaceutical formulations. Journal of Applied Pharmaceutical Science, 4(12). 001 -007. DOI: 10.7324/JAPS.2014.41201
  2. Ofori-Kwakye K, Obese E, Boakye-Gyasi, ME. (2013). Formulation and in-vitro evaluation of sustained release diclofenac sodium matrix tablets using blends of cashew gum, xanthan gum and hydroxypropylmethylcellulose as hydrophilic drug release modifiers. Indian Journal of Novel Drug Delivery 5(4), 187 – 197.
  3. El-Duah M, Ofori-Kwakye K. (2012). Substandard artemisinin-based antimalarial medicines in licensed retail pharmaceutical outlets in Ghana. Journal of Vector Borne Diseases 49, 131 – 139.
  4. Ofori-kwakye K, Kwapong AA, Bayor MT. (2011). Wound healing potential of methanol extract of Spathodea campanulatastem bark formulated into a topical preparation. African Journal of Traditional, Complementary and Alternative Medicine 8 (3), 218 – 223.
  1. Kumadoh D, Adotey J, Ofori-Kwakye K, Kipo SL, Prah T, Patterson S. (2014). Formulation of oral capsules from asena herbal decoction used traditionally in Ghana for the treatment of arthritis. World Journal of Pharmacy and Pharmaceutical Sciences, 3(7), 1824 – 1833.
  2. Ofori-Kwakye K, Ayensu I, Akyinah B, Kipo SL, Boakye-Gyasi ML. (2014). Adulteration of Ghanaian topical herbal preparations with dexamethasone. World Journal of Pharmacy and Pharmaceutical Sciences, 3(6), 134 – 141.
  1. Ofori-Kwakye K, Amekyeh H, El-Duah M, Kipo SL. (2012). Mechanical and tablet coating properties of cashew tree (Anacardium occidentale L) gum-based films. Asian Journal of Pharmaceutical and Clinical Research 5 (4), 62 – 68.
  1. Bediako A, Adotey J, Ofori-Kwakye K. (2011). Pharmacokinetics of amodiaquine after a single oral dose in Ghanaian children with uncomplicated malaria. Journal of Pharmaceutical Sciences and Research 3 (8), 1420 – 1426.
  2. Asantewaa Y, Ofori-Kwakye K, Kipo SL, Boamah VE, Johnson R. (2011). Investigation of the emulsifying and suspending potential of cashew tree gum in pharmaceutical formulations. International Journal of Pharmacy and Pharmaceutical Sciences 3 (4), 215 - 219.
  3. Kobierski S, Ofori-Kwakye K, Müller RH, Keck CM. (2011). Resveratrol nanosuspensions: interaction of preservatives with nanocrystal production. Die Pharmazie 66, 942 – 947. DOI: 10.1691/ph.2011.1038

 

  1. Boamah VE, Gbedema SY, Adu F, Ofori-Kwakye K. (2011). Microbial quality of household water sources and incidence of diarrhoea in three peri-urban communities in Kumasi, Ghana. Journal of Pharmaceutical Sciences and Research 3 (3), 1087 – 1092.
  2. Bayor MT, Kipo SL, Ofori-Kwakye K. (2010). The accuracy and quality of household spoons and enclosed dosing devices used in the administration of oral liquid medications in Ghana. International Journal of Pharmacy and Pharmaceutical Sciences 2 (Suppl.1), 150 – 153.
  3. Kobierski S, Ofori-Kwakye K, Müller RH, Keck CM. (2009). Resveratrol nanosuspensions for dermal application – production, characterization and physical stability. Die Pharmazie 64 (11), 741 - 747. DOI: 10.1691/ph.2009.9097
  1. Ofori-Kwakye K, Asantewaa Y, Kipo SL. (2010). Physicochemical and binding properties of cashew tree gum in metronidazole tablet formulations. International Journal of Pharmacy and Pharmaceutical Sciences 2 (4), 105 - 109.
  2. Ofori-Kwakye K, Osei-Yeboah F, Kipo SL. (2010). Formulation and quality evaluation of two conventional release tablet formulations. International Journal of Pharmaceutical Sciences Review and Research 4 (1), 94 – 99.
  1. Ofori-Kwakye K, Adom ENN, Kipo SL. (2009). Preparation and in vitro characteristics of tablet cores coated with albizia, albizia/khaya and albizia/HPMC films. International Journal of Applied Pharmaceutics 1 (1), 22 - 29.

 

  1. Ofori-Kwakye K, Kwapong AA, Adu F. (2009). Antimicrobial activity of extracts and topical products of the stem bark of Spathodea campanulata for wound healing. African Journal of Traditional, Complementary and Alternative Medicine 6 (2), 168 – 174.

 

  1. Ofori-Kwakye K, Asantewaa Y, Gaye O. (2008). Quality of artesunate tablets sold in pharmacies in Kumasi, Ghana. Tropical Journal of Pharmaceutical Research 7 (4), 1179 – 1184.

 

  1. Ofori-Kwakye K, Adom ENN. (2007). Mechanical properties of khaya and albizai films intended for pharmaceutical coating. Journal of Ghana Science Association 9 (2), 43 – 53. DOI: 10.4314/jgsa.v9i2.18013

 

  1. Kuntworbe N, Adotey J, Ofori-Kwakye K, Kipo SL. (2006). Formulation and evaluation of a combined chloroquine phosphate and chlorpheniramine maleate product. Journal of Science and Technology (Ghana) 26 (3), 32 – 39. DOI: 10.4314/just.v26i3.33002

 

  1. Dwomo-Fokuo Y, Owusu-Antwi R, Ofori-Kwakye K. (2006). Locally derived starches as potential alternative tablet disintegrant and binder sources. Ghana Pharmaceutical Journal 32 (1), 43 – 48.

 

  1. Ofori-Kwakye K, Fell JT, Kipo SL. (2006). Effects of pH of medium and molecular weight on polyelectrolyte complex formation between pectin and chitosan. Journal of Science and Technology (Ghana), 26 (2), 66 – 73. DOI: 10.4314/just.v26i2.32990

 

  1. Ofori-Kwakye K, Kipo,wakye,,mo-Fokuo Y.ERSITY) SL, Fell JT. (2006). Colonic drug delivery and absorption. Ghana Pharmaceutical Journal 31 (1), 49 – 64.

 

  1. Ofori-Kwakye K, Martin, GP. (2005). Viscoelastic characterization of alginate gels intended for wound healing. Journal of Science and Technology (Ghana) 25 (2), 46 – 52. DOI: 10.4314/just.v25i2.32946

 

  1. Ofori-Kwakye K, Fell JT. (2005). Effect of mixed film coating on pharmacokinetics of paracetamol tablets. Journal of Science and Technology (Ghana) 25 (1), 25 – 32. DOI: 10.4314/just.v25i1.32929
  1. Ofori-Kwakye K, Fell JT, Sharma HL, Smith A-M. (2004). Gamma scintigraphic evaluation of film-coated tablets intended for colonic or biphasic release. International Journal of Pharmaceutics 270, 307 – 313. DOI:10.1016/j.ijpharm.2003.11.009
  2. Ofori-Kwakye K, Fell JT. (2003). Leaching of pectin from mixed films containing pectin, chitosan and HPMC intended for biphasic drug delivery. International Journal of Pharmaceutics 250, 251 – 257. DOI:10.1016/S0378-5173(02)00546-X
  3. Ofori-Kwakye K, Fell JT. (2003). Biphasic drug release from film-coated tablets. International Journal of Pharmaceutics 250, 431 – 440. DOI:10.1016/S0378-5173(02)00578-1
  4. Ofori-Kwakye K, Fell JT. (2001). Biphasic drug release: the permeability of films containing pectin, chitosan and HPMC. International Journal of Pharmaceutics 226, 139 – 145. DOI:10.1016/S0378-5173(01)00802-X
  5. Ofori-Kwakye K, Fell JT. (2001). Biphasic drug release from film-coated tablets. Science proceedings of the British Pharmaceutical Conference: 276.
  6. Ofori-Kwakye K, Fell JT. (2000). Permeability of pectin/chitosan/HPMC films intended for colonic or bimodal drug delivery. Journal of Pharmacy and Pharmacology 52, (Supplement): 172.

 

Selected Conference Proceedings

  1. Ofori-Kwakye K, Mfoafo KA, Kipo SL, Kuntworbe N, Boakye-Gyasi ME. (2015). Characterization of natural gum-based extended release matrix tablets of two model drugs by direct compression. Pharma Middle East, November 02-04, Dubai, UAE.

 

  1. Mfoafo KA, Ofori-Kwakye, K. (2013). The use of the SeDeM diagram expert system to determine the suitability of cashew gum as a direct compression excipient for tablets. 5th Annual Scientific Conference, College of Health Sciences ‘Trends in cancer research and management’, CCB Auditorium, KNUST, Kumasi, November 14 -15, B15, pp. 89 – 90.
  2. El-Duah M, Ofori-Kwakye K. (2011). Prevalence of artemisinin-based combination therapy medication in licensed premises in Kumasi Metropolis. 4th Annual Scientific Conference, College of Health Sciences ‘Managing infectious  diseases – trends and challenges’, Great Hall, KNUST, Kumasi, September 1 -2, B11, pp. 30 – 31.
  3. El-Duah M, Ofori-Kwakye K. (2011). Quality of artemisinin-based antimalarials in licensed premises in Kumasi Metropolis. 4th Annual Scientific Conference, College of Health Sciences ‘Managing infectious  diseases – trends and challenges’, Great Hall, KNUST, Kumasi, September 1 -2, B11, pp. 49 – 50.
  4. Kobierski S, Ofori-Kwakye K, Müller RH. (2011). Applying different diminution techniques for production of resveratrol nanosuspensions. Polish-German Symposium on Pharmaceutical Sciences ‘Perspectives for a new decade’, Dusseldorf, Germany, May 20 – 21, p. 104.
  5. Kobierski S, Ofori-Kwakye K, Müller RH, Keck CM. (2009). Optimized production of preserved resveratrol nanosuspensions. 36th Annual Meeting & Exposition of the Controlled Release Society (CRS), July 18 – 22, Copenhagen, Denmark.

 

  1. Arhin-Sam VE, Boakye-Yiadom K, Ofori-Kwakye K, Adu F, Gbedema SY. (2009). Groundwater quality in some communities in Kumasi, Ghana, and the effectiveness of ten anti-diarrhoeal agents against isolated organisms. 10th CPA/ 74th PSGH Conference, Accra, Ghana (5 – 9 August) p. 114.

 

  1. Bayor MT, Kipo SL, Ofori-Kwakye K. (2009). The accuracy and quality of household spoons and enclosed devises used in the administration of oral liquid medications in Ghana. 2nd Scientific Conference, College of Health Sciences, KNUST, Kumasi, Ghana (10 – 11 September) pp. 40 – 41.

 

  1. Kuntworbe N, Ofori-Kwakye K, Mensah F. (2008). Quality assessment of information on labels of herbal products in Ghana. 3rd Regional Conference of the West Africa Network of Natural Products Research Scientists (WANNPRES), Ouagadougou (6 – 9 August), pp. 24 – 25.

 

  1. Ofori-Kwakye K, Fell JT. (2006). Assessing the influence of pH and molecular weight on polyelectrolyte complexation involving chitosan and pectin. 10th Iranian Pharmaceutical Sciences Conference, Teheran, Iran, (21-24 August).

 

  1. Ofori-Kwakye K, Kipo SL, Nyantakyi DA. (2006). There is a high incidence of tablet-splitting among patients in Ghana. 10thIranian Pharmaceutical Sciences Conference, Teheran, Iran, (21-24 August).

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