Prof Prof. Adosraku Reimmel Kwame
(Associate Professor) B.Pharm, M.Phil (Kumasi), Ph.D (London),.
Has first degree in Pharmacy and M.Phil in Phyto-Analytical Chemistry at KNUST, Kumasi. Obtained PhD degree in NMR studies of membrane phospholipids and phosphonolipids isolated from tropical parasites at the University of London School of Pharmacy, the premier Pharmacy School in the United Kingdom.
Recently, I served on the West African Health Organisation (WAHO) Expert Committee that developed Drug Quality Documents to be used in ECOWAS for the assessment of the quality of medicines produced or used in the region.
This committee also inspected National Medicines Laboratories in the countries of West Africa and submitted technical reports to WAHO. In advancing research, Reimmel introduced the payment of bench fees in this department (adopted by the university years later). This greatly contributed to the acquisition and maintenance of hplc instruments and supplies critical to research activities in the department. Experienced in hplc use and basic maintenance.
Research interests include:
Phytomedicines – isolation, purification and bioactivity of medicinally important compounds from plants, their stability and quantification using hplc.
Drug Quality Analysis - involving hplc method development for the separation and quantification of actives, stability and bioequivalence assessment of formulated drug products.
Selected Publications: (Co-authored)
- Proton nmr lipid profile of Leishmania donovani promastigotes, Molecular and Biochemical Parasitology, 1993, 62, 251-262.
- Tetrahymena thermophyla: Analysis of phospholipids and phosphonolipids by high field 1-H NMR, Biochimica et Biophysica Acta, 1996, 1299, 167 – 174.
- An hplc method for the direct assay of serotonin precursor, 5-hydroxytryptophan in the seeds of Griffonia simplicifolia, Phytochemical Analysis, 2002, 13, 333 – 337.
- Post-harvest stability of 5-hydroxytryptophan in Griffonia simplicifolia seeds, International Journal of Pure and Applied Chemistry, 2006, 1(1), 129-131.
- Determining the bioequivalence of paracetamol products with urinary excretion data, West African Journal of Pharmacy, 2007, 20(1), 14 – 22.
- Characterisation and Hplc quantification of Xylopic Acid in the dried fruits of Xylopia aethiopica, International Journal of Pure and Applied Chemistry, 2011, 6(2)